How Pelleve works at the cellular level

Pelleve precisely targets the subdermal junction

• Radio frequency surgical equipment emits energy in the form of electromagnetic waves, which are absorbed by the surrounding tissue, creating a heated treatment zone
• Increased resistance causes heat buildup at the subdermal junction
• Heat induces collagen denaturization, followed by collagen contraction
• Collagen breaks down
• Protein stimulation causes new collagen formation and production in the dermis
• Existing bands of collagen tighten in subcutaneous fat
• Remodeling of collagen occurs in dermis and subcutaneous fat, creating a superficial tightening of the epidermis

Pelleve is indicated for the non-ablative treatment of mild to moderate facial wrinkles for skin phototypes I-IV. Possible side effects of Pelleve are usually treatment-site related and include mild discomfort during the procedure localized within the treatment area. Mild swelling and redness may occur which typically go away within 2 to 24 hours.